NYSBC scientists pursue fundamental questions in structural biology, developing technologies and methods that advance the field. Research programs span RNA biology, cryo-EM innovation, and NMR methods development.
The New York Structural Biology Center, founded more than 25 years ago as a shared resource for nine leading New York research institutions, is a global leader in structural biology research. NYSBC houses an unparalleled suite of instrumentation, with cryo-electron and NMR platforms that are among the world’s largest and most advanced, and the NYX beamline at Brookhaven National Laboratory. Combined with NYSBC’s methodological innovations, this instrumentation gives researchers worldwide access to tools that drive significant biological discoveries.
Services
Delivering data that drives discovery
NYSBC provides researchers with access to advanced cryo-electron microscopy, NMR spectroscopy, and X-ray crystallography platforms.
In addition to state-of-the-art instrumentation, NYSBC offers deep technical expertise to ensure researchers’ needs are met. Among other services, staff advise and train scientists, collaborate on developing workflows, and take on contract work across the structural biology spectrum, ranging from gene cloning to structure determination.
For access, scientists from member institutions schedule time directly with NYSBC. Non-member researchers have the opportunity to access NHSBC resources through processes described on the individual equipment pages.
Electron Microscopy
One of the world’s largest cryo-electron microscopy fleets, spanning single-particle imaging, tomography, and in situ methods.
ACCESS
Members
NCCAT
NCITU
X-Ray Crystallography
Home to NYX, a high-throughput beamline at the National Synchrotron Light Source II (NSLS-II).
ACCESS
Members
Proprietary
Nuclear Magnetic Resonance Spectroscopy
High-field spectrometers spanning 475–900 MHz, resolving molecular structure and dynamics.
ACCESS
Members
Proprietary
Special Projects Group
A full gene-to-structure pipeline, delivering protein production and structural biology expertise to outside investigators.
ACCESS
Members
Proprietary
Member Institutions
Partnering with New York’s foremost research and medical organizations
